Emerging treatments for bronchiectasis in 2025

emerging treatments bronchiectasis

Bronchiectasis care is changing. For years, treatment focused on airway clearance, infection control and preventing flares. In 2025, targeted medicines are arriving, with more in late-stage research. This guide explains how the key emerging treatments for bronchiectasis work, who might benefit, and how they fit alongside standard UK care. The big news: the first approved […]

Bronchiectasis in Immunocompromised Individuals

Bronchiectasis in Immunocompromised individuals

Bronchiectasis in immunocompromised individuals is a serious health issue. It develops when the airways become permanently widened and scarred after repeated infections. This lung damage makes it harder to clear mucus, leading to even more infections. The result is a vicious cycle of illness that can seriously reduce quality of life. Understanding why immunocompromised people […]

Bronchiectasis Diet: Evidence-Based Nutritional Tips

Bronchiectasis diet

What is Bronchiectasis & Why Nutrition Matters Bronchiectasis is a chronic lung condition where airways are permanently dilated, leading to frequent infections, inflammation, mucus build-up, and damage. Because of this: Evidence for Key Dietary / Micronutrient Factors in Bronchiectasis Here are what the studies show about specific nutrients & dietary patterns in bronchiectasis. Nutrient / […]

Living with Bronchiectasis and Co-Morbidities

broncehiectasis and co-morbidities

Living with bronchiectasis can be challenging, especially when other conditions such as asthma, COPD, GERD, chronic rhinosinusitis, rheumatoid arthritis, allergic bronchopulmonary aspergillosis (ABPA), or nontuberculous mycobacterial (NTM) lung disease are also present. These co-morbidities often overlap in symptoms and complicate both diagnosis and treatment. This guide looks at the latest evidence-based strategies for managing these […]

Brensocatib: Is this breakthrough a Game-Changer for Bronchiectasis?

Brensocatib for bronchiectasis

Brensocatib is making waves in respiratory medicine. Following the full publication of its Phase 3 ASPEN trial in The New England Journal of Medicine in May 2025, this new oral treatment is being hailed as a breakthrough for people living with non-cystic fibrosis bronchiectasis (NCFBE). On 12 August 2025, the U.S FDA approved Brensocatib for […]

Environmental factors in NTM infections

ntm environmental factors

Nontuberculous mycobacteria (NTM) infections are an increasing public health challenge globally, and environmental factors play a significant role in this rise. NTM are opportunistic pathogens found in diverse habitats such as soil, water systems, and even household plumbing. Unlike Mycobacterium tuberculosis, NTM are not thought to spread from person to person but through environmental exposure. […]

Fatigue in Bronchiectasis: Understanding and Managing a Debilitating Symptom

fatigue in bronchiectasis

Bronchiectasis is a chronic lung condition characterised by the permanent enlargement of parts of the airways, leading to a cycle of inflammation, infection, and progressive lung damage. While the hallmark symptoms of bronchiectasis include chronic cough, excessive sputum production, and recurrent lung infections, fatigue is a lesser-known yet profoundly debilitating symptom that significantly impacts patients’ […]

Managing Refractory MAC Pulmonary Disease

Treatment of Refractory MAC pulmonary disease

Mycobacterium avium complex (MAC) pulmonary disease is a challenging condition to treat, particularly when standard therapies fail. When patients continue to test positive for MAC despite undergoing treatment, the disease is considered refractory. Here we will explore what refractory MAC pulmonary disease is, how it’s diagnosed, and the steps that can be taken to try […]

Understanding and Managing the Treatment Burden in Bronchiectasis

Treatment burden in bronchiectasis

Managing bronchiectasis can be highly burdensome, affecting both physical and mental health. Here we explore the treatment burden in bronchiectasis and provides practical strategies to cope with the challenges it poses. The Challenge of Treatment Burden in Bronchiectasis Daily Management and Routine People with bronchiectasis often endure a complex daily routine of medications, physical therapy, […]

Bronchiectasis Consultation: Key Symptoms and Essential Information for Your Doctor

Bronchiectasis consultation

Bronchiectasis is a chronic respiratory disease where the airways widen abnormally, trapping mucus and causing persistent infections. Recognising symptoms early and discussing them accurately with your doctor is crucial for effective management. This article will explore the essential information that you have to let your doctor know when having a bronchiectasis consultation with your specialist. […]

Nebulised Antibiotics in Non-CF Bronchiectasis

Man with bronchiectasis using nebulised antibiotics

Bronchiectasis, a chronic lung condition characterised by widened and damaged airways, can be a challenging beast to tame. But here’s a ray of hope – nebulised antibiotics. They’ve emerged as a game-changer, especially for those with non-cystic fibrosis (non-CF) bronchiectasis. This article looks into the world of nebulised antibiotics like Colomycin, Gentamicin, Aztreonam, Tobramycin, and […]

Introduction to Primary Ciliary Dyskinesia (PCD)

Primary ciliary dyskinesia

What is PCD? Primary Ciliary Dyskinesia (PCD) is a rare congenital condition, primarily characterised by dysfunction in the cilia, the tiny hair-like structures that line our respiratory tract. These cilia serve as essential movers, propelling mucus and foreign particles out of our respiratory passages. Imagine a conveyor belt system in a large factory—when it breaks […]

The Future of Pneumonia Diagnosis and Treatment

Pneumonia diagnosis

Introduction No one likes being sick, right? But when it comes to pneumonia, it’s not just an “under-the-weather” scenario—it’s potentially life-threatening. However, in the fast-evolving world of medical science, there’s an uplifting twist! With a rapid evolution in technology and research, the future of pneumonia diagnosis and treatment is set to revolutionize patient care. So, […]

Who Should Have the Pneumococcal Vaccine?

Pneumococcal Vaccine

The pneumococcal vaccine, often colloquially referred to as the pneumonia vaccine, plays an integral role in the prevention of diseases caused by the Streptococcus pneumoniae bacteria. However, it’s important to remember that this particular bacterium is not the only cause of pneumonia, a common misconception. What is the Pneumococcal Vaccine The pneumococcal vaccine targets Streptococcus […]

Phages in Bronchiectasis Treatment: A Revolutionary Approach?

Phages in bronchiectasis

The Burden of Bronchiectasis Bronchiectasis presents a significant health challenge worldwide. This condition is characterised by a permanent enlargement of the airways. It results in a chronic cough, fatigue, and persistent chest infections. Current treatments help manage symptoms and control infection but do not offer a permanent solution to the presence of colonising bacteria. However, […]

Comprehensive Guide to NTM Treatment: Key Medications Explained

NTM medication

Non-tuberculous Mycobacteria (NTM) infections present a significant public health concern globally. NTM, unlike tuberculosis, aren’t transmitted from person to person. However, they can cause severe lung disease, particularly in individuals with pre-existing respiratory conditions. Accurate diagnosis and effective treatment are vital in managing these infections. With an increasing number of cases each year, understanding NTM […]

Understanding Bronchiectasis: A Look into its Complications

Bronchiectasis complications

The world of respiratory health presents many challenges, and this includes the complications of bronchiectasis. Bronchiectasis is a condition, characterised by the permanent enlargement of the bronchial tubes, and is often debilitating. This blog highlights some of the important complications of bronchiectasis, with a focus on bacterial colonisation, frequent exacerbations, non-tuberculous mycobacteria (NTM) infections, fungal […]

Finding Your Best Bronchiectasis Doctor and Treatment Strategies

Cystic Bronchiectasis

Finding the best bronchiectasis doctor to help you manage your condition isn’t easy. This is particularly important when your condition is more complicated, you have a higher symptom burden or frequent infections. Breathing easy might seem an unremarkable feat to most, but for individuals suffering from bronchiectasis, it’s a daily battle. This long-term condition causes […]

Treatment of bronchiectasis: What should I know?

lady with bronchiectasis using nebuliser - DR Ricardo Jose - chest doctor

What is bronchiectasis? Before discussing the treatment of bronchiectasis it is important to understand what bronchiectasis is and how it affects people. Bronchiectasis is a condition where there is abnormal dilation of the bronchi. There are several medical conditions that lead to this condition and need to be considered when treating people with bronchiectasis. However, […]

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